Volume 73, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


Following increasing reinfestation with after insecticide spraying, the household incidence of infection with in children was positively related to the domestic abundance of infected and the presence or proportion of infected dogs or cats in Amamá, a rural village in northwestern Argentina. Seven (12.1%) children seronegative for antibodies to at baseline, with no history of travel or blood transfusion, seroconverted after three years. Six incident cases lived in houses heavily infested with , with high proportions of bugs infected with and having fed on humans or dogs. The remaining incident case occurred under a very light domestic infestation detected only at the endpoint, and most bugs had fed on humans. Dogs had a 17 times greater force of infection than children (4.3% per year). Sustained vector surveillance is crucially needed in high-risk areas for Chagas disease such as the Gran Chaco.


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  • Received : 18 Nov 2004
  • Accepted : 16 Dec 2004

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