Volume 73, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


Malaria kills more than one million people a year, and understanding the historical association between its most notorious causative agent, , and its mosquito vectors is important in fighting the disease. We present a phylogenetic analysis of a number of species within the mosquito subgenus based on a selection of mitochondrial and nuclear genes. Although some of these relationships have been estimated in other studies, generally few species were included and/or statistical support at many nodes was low. Here we include two additional species of anthropophilic malaria vectors and reanalyze these relationships using a Bayesian method that allows us to simultaneously incorporate different models of evolution. We report data that indicate a paraphyletic relationship between five anthropophilic African mosquito vectors. Such a relationship suggests that these species can serve as independent natural experiments for anopheline immunologic responses to regular, prolonged contact with .


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  • Received : 05 Feb 2005
  • Accepted : 24 May 2005

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