Volume 73, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


Few data exist on the relative importance of individual species in acquired immunodeficiency syndrome cryptosporidiosis. We characterized 127 inpatients infected with human immunodeficiency virus (HIV) in Tanzania for their CD4 cell count and by stool analysis, including immunofluorescence and polymerase chain reaction-restriction fragment length polymorphism. was detected in patients both with and without diarrheal symptoms (defined as ≥ 3 liquid stools/day, 11 of 61 versus 11 of 66; = not significant) and was a marker for low CD4 cell count (median = 124/μL versus 212/μL in -negative patients; < 0.04). was the predominant species in this region and was associated with a longer duration of symptoms, a higher rate of asymptomatic infection, and a lower CD4 cell count versus -infected patients ( < 0.05). This study suggests there may be important differences in the natural history of infection in HIV-infected persons depending on parasite species.


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  • Received : 23 Jun 2004
  • Accepted : 11 Nov 2004

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