1921
Volume 73, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Cysticercosis due to infection is endemic in developing countries of the Americas, Asia, and Africa. This study was designed to establish the prevalence of cysticercosis in 158 inpatients of a psychiatric institution in the state of Tachira (Venezuela) and in 127 healthy control subjects. Positive blood tests for cysticercosis by Western blotting were recorded in 18.35% of the patients and in 1.57% of the controls. Individuals with mental retardation were found to carry an increased risk of cysticercosis (RR: 2.92; 1.22 < 2.92 > 7.0; < 0.05) compared with patients with other psychiatric disorders. Taeniasis by spp. was not demonstrated in the patient group, although a high incidence of infection by other helminths (95.1%) was detected. The high prevalence of cysticercosis in the psychiatric inpatient group, compared with healthy individuals, and the lack of a differential diagnosis of neurocysticercosis suggest cerebral cysticercosis in a large proportion of these patients. Cysticercosis could be the origin of the psychiatric disorders of these patients and may also be due to contact with the parasite in an environment with poor hygiene conditions and a deficient health care system.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.2005.73.504
2005-09-01
2017-11-23
Loading full text...

Full text loading...

/deliver/fulltext/14761645/73/3/0730504.html?itemId=/content/journals/10.4269/ajtmh.2005.73.504&mimeType=html&fmt=ahah

References

  1. Sarti E, 1997. Taeniasis and cysticercosis due to Taenia solium. Salud Publica Mex 39 : 225–231.
  2. Del Brutto OH, Sotelo J, 1988. Neurocysticercosis: an update. Rev Infect Dis 10 : 1075–1087.
  3. Ohsaki Y, Matsumoto A, Miyamoto K, Kondoh N, Araki K, Ito A, Kikuchi K, 1999. Neurocysticercosis without detectable specific antibody. Intern Med 38 : 67–70.
  4. Ostrosky-Zeichner L, Estanol B, 1999. Immunopathogenesis of neurocysticercosis: is damage mediated by the host immune response? Int J Parasitol 29 : 649–650.
  5. Flisser A, 1994. Taeniasis and cysticercosis due to Taenia solium. Prog Clin Parasitol 4 : 77–116.
  6. Flisser A, 1987. Host-parasite relations in human and porcine cysticercosis. Gac Med Mex 123 : 157–164.
  7. Takayanagui OM, Jardim E, 1992. Therapy for neurocysticercosis. Comparison between albendazole and praziquantel. Arch Neurol 49 : 290–294.
  8. Roman G, Sotelo J, Del Brutto O, Flisser A, Dumas M, Wadia N, Botero D, Cruz M, Garcia H, de Bittencourt PR, Trelles L, Arriagada C, Lorenzana P, Nash TE, Spina-Franca A, 2000. A proposal to declare neurocysticercosis an international reportable disease. Bull World Health Organ 78 : 399–406.
  9. White AC Jr, Atmar RL, 2002. Infections in Hispanic immigrants. Clin Infect Dis 34 : 1627–1632.
  10. Pal DK, Carpio A, Sander JW, 2000. Neurocysticercosis and epilepsy in developing countries. J Neurol Neurosurg Psychiatry 68 : 137–143.
  11. Webbe G, 1994. Human cysticercosis: parasitology, pathology, clinical manifestations and available treatment. Pharmacol Ther 64 : 175–200.
  12. Richards F Jr, Schantz PM, 1991. Laboratory diagnosis of cysticercosis. Clin Lab Med 11 : 1011–1028.
  13. Creasy JL, Alarcon JJ, 1994. Magnetic resonance imaging of neurocysticercosis. Top Magn Reson Imaging 6 : 59–68.
  14. Ev LV, Maia AA, Pianetti G, Nascimento E, 1999. Immunological evaluation of a 26-kDa antigen from Taenia solium larvae for specific immunodiagnosis of human neurocysticercosis. Parasitol Res 85 : 98–102.
  15. Reparon C, Jansen J, Bruck W, Verheggen R, Zimmerer B, 1999. A case of neurocysticercosis-differential diagnostic aspects. Funct Neurol 14 : 37–41.
  16. White AC Jr, 2000. Neurocysticercosis: updates on epidemiology, pathogenesis, diagnosis, and management. Annu Rev Med 51 : 187–206.
  17. Kalra V, Sethi A, 1992. Childhood neurocysticercosis–epidemiology, diagnosis and course. Acta Paediatr Jpn 34 : 365–370.
  18. Tsang V, Wilson M, 1995. Taenia solium cysticercosis: An under-recognized but serious public health problem. Parasitology Today 11 : 124–126.
  19. Scharf D, 1988. Neurocysticercosis. Two hundred thirty-eight cases from a California hospital. Arch Neurol 45 : 777–780.
  20. Signore RJ, Lahmeyer HW, 1988. Acute psychosis in a patient with cerebral cysticercosis. Psychosomatics 29 : 106–108.
  21. Forlenza OV, Filho AH, Nobrega JP, dos Ramos Machado L, de Barros NG, de Camargo CH, da Silva MF, 1997. Psychiatric manifestations of neurocysticercosis: a study of 38 patients from a neurology clinic in Brazil. J Neurol Neurosurg Psychiatry 62 : 612–616.
  22. Takayanagui OM, Leite JP, 2001. Neurocysticercosis. Rev Soc Bras Med Trop 34 : 283–290.
  23. Tavares AR Jr, 1993. Psychiatric disorders in neurocysticercosis. Br J Psychiatry 163 : 839.
  24. American Psychiatric Association, American Psychiatric Association. Work Group to Revise DSM-III, 1987. Diagnostic and Statistical Manual of Mental Disorders: DSM-III-R. Washington, DC: American Psychiatric Association.
  25. Rossi N, Rivas I, Hernandez M, Urdaneta H, 2000. Immunodiagnosis of neurocysticercosis comparative study of antigenic extracts from Cysticercus cellulosae and Taenia crassiceps. Rev Cubana Med Trop 52 : 157–164.
  26. Vaz AJ, Nunes CM, Piazza RM, Livramento JA, Da Silva MV, Nakamura PM, Ferreira AW, 1997. Immunoblot with cerebrospinal fluid from patients with neurocysticercosis using antigen from cysticerci of Taenia solium and Taenia crassiceps. Am J Trop Med Hyg 57 : 354–357.
  27. Tsang VC, Brand JA, Boyer AE, 1989. An enzyme-linked immunoelectrotransfer blot assay and glycoprotein antigens for diagnosing human cysticercosis (Taenia solium). J Infect Dis 159 : 50–59.
  28. Ritchie L, 1948. An ether sedimentation technique for routine stool examination. Bull. US Army Med. Dept 8 : 326.
  29. Mendez-Castellano H, 1986. Estratificación social y biología humana. Método de Graffar modificado. Arch Ven Puer Ped 49 : 93–110.
  30. Sarti E, Schantz PM, Plancarte A, Wilson M, Gutierrez IO, Lopez AS, Roberts J, Flisser A, 1992. Prevalence and risk factors for Taenia solium taeniasis and cysticercosis in humans and pigs in a village in Morelos, Mexico. Am J Trop Med Hyg 46 : 677–685.
  31. Larralde C, Padilla A, Hernandez M, Govezensky T, Sciutto E, Gutierrez G, Tapia-Conyer R, Salvatierra B, Sepulveda J, 1992. Seroepidemiology of cysticercosis in Mexico. Salud Publica Mex 34 : 197–210.
  32. Diaz Camacho S, Candil Ruiz A, Uribe Beltran M, Willms K, 1990. Serology as an indicator of Taenia solium tapeworm infections in a rural community in Mexico. Trans R Soc Trop Med Hyg 84 : 563–566.
  33. Bern C, Garcia HH, Evans C, Gonzalez AE, Verastegui M, Tsang VC, Gilman RH, 1999. Magnitude of the disease burden from neurocysticercosis in a developing country. Clin Infect Dis 29 : 1203–1209.
  34. Garcia HH, Gilman RH, Catacora M, Verastegui M, Gonzalez AE, Tsang VC, 1997. Serologic evolution of neurocysticercosis patients after antiparasitic therapy. Cysticercosis Working Group in Peru. J Infect Dis 175 : 486–489.
  35. Garcia HH, Gonzalez AE, Gilman RH, Palacios LG, Jimenez I, Rodriguez S, Verastegui M, Wilkins P, Tsang VC, 2001. Short report: transient antibody response in Taenia solium infection in field conditions-a major contributor to high seroprevalence. Am J Trop Med Hyg 65 : 31–32.
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.2005.73.504
Loading
/content/journals/10.4269/ajtmh.2005.73.504
Loading

Data & Media loading...

  • Received : 28 Aug 2004
  • Accepted : 06 Apr 2005

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error