Volume 73, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


In 2002, population- and treatment center–based surveillance was used to study the disease burden of shigellosis in rural Hebei Province in the People’s Republic of China. A total of 10,105 children with diarrhea or dysentery were enrolled. Infants were treated most frequently for diarrhea (1,388/1,000/year) followed by children ≤ 5 years old (618/1,000/year). Shigellosis was treated most often in children 3–4 years old (32/1,000/year) and people > 60 years of age (7/1,000/year). Fifty-six percent (184 of 331) isolates were detected in patients who had non-bloody diarrhea. was identified in 93% of 306 isolates. The most common serotypes were 1a (34%), X (33%), and 2a (28%). More than 90% of the isolates were resistant to cotrimoxazole and nalidixic acid, but remained susceptible to ciprofloxacin, norfloxacin, and gentamicin. Widespread resistance to antibiotics adds urgency to the development and use of vaccines to control shigellosis.


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  • Received : 07 Sep 2004
  • Accepted : 28 Feb 2005

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