Volume 73, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


The prevalence of chloroquine (CQ) treatment failure and the genotype failure index was determined in four sentinel sites in Burkina Faso. In three sites, the genotype failure index varied between 1.7 and 3, a result confirming the relationship between the CQ resistance transporter () T76 mutation and CQ resistance. In the remaining site, the genotype failure index was unusually low, 1.1, which was significantly different than that in the other sites ( < 0.00001). These findings are discussed. Often but not always, the prevalence of CQ resistance can be correctly estimated by the T76 genotype failure index.


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  • Received : 12 Jul 2004
  • Accepted : 20 Dec 2004

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