1921
Volume 72, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Studies with animal models have suggested the possibility of interactions between parasites during concurrent infections and have raised the question of a similar phenomenon in humans. The present survey was undertaken to assess the impact of urinary schistosomiasis on the susceptibility of children to malaria. It was carried out in Senegal between September 2001 and March 2002 among 523 children 3–15 years of age. We tested the association between densities and the load of egg excretion using a linear mixed model because data were not independent. After controlling for age, sex, and season, we showed that children lightly infected with (1–9 eggs/10 mL of urine) had lower densities than those not infected (β = −0.34, 95% confidence interval = −0.85, −0.10), suggesting a negative interaction between both parasites.

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2005-06-01
2017-11-20
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  • Received : 16 Jul 2004
  • Accepted : 23 Dec 2004

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