1921
Volume 72, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

To assess the clinical findings associated with detection of adult worms on ultrasound, 186 schoolchildren in a filariasis-endemic area of Haiti underwent physical and ultrasonographic examinations. The filaria dance sign (FDS) of adult was detected in the inguinal and crural lymphatics of 28 (15%) children. FDS detection was more common in older children ( = 0.003) and in those with a history of inguinal lymph node inflammation ( = 0.002) or crural lymphadenopathy on physical exam ( = 0.01). Twenty-five FDS-positive children were reexamined after three annual cycles of mass treatment for lymphatic filariasis (LF). The total number of adult worm nests detected by ultrasound decreased from 29 to 4 ( ≤0.0001). FDS and lymphangiectasia were detected in the intrascrotal ( = 3) and inguinal ( = 1) lymphatic vessels of three postpubescent boys. This study demonstrates clinical and subclinical findings of LF in FDS-positive children.

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References

  1. World Health Organization, 1995. Bridging the gaps. The World Health Report. WHO, Geneva, Switzerland.
  2. Anonymous, 1997. Lymphatic filariasis in the Americas. Epidemiol Bull 18 : 6–7. [Google Scholar]
  3. Ottesen EA, Duke BOL, Karam M, Behbehani K, 1997. Strategies and tools for the control/ elimination of lymphatic filariasis. Bull World Health Organ 75 : 491–503. [Google Scholar]
  4. Michael E, Bundy DAP, Grenfell BT, 1996. Re-assessing the global prevalence and distribution of lymphatic filariasis. Parasitology 112 : 409–428. [Google Scholar]
  5. Eberhard ML, Walker EM, Addiss DG, Lammie PL, 1996. A survey of knowledge, attitudes, and perceptions (KAPs) of lymphatic filariasis, elephantiasis, and hydrocele among residents in an endemic area in Haiti. Am J Trop Med Hyg 54 : 299–303. [Google Scholar]
  6. Lammie PJ, Hightower AW, Eberhard ML, 1994. The age-specific prevalence of antigenemia in a Wuchereria bancrofti-exposed population. Am J Trop Med Hyg 51 : 348–355. [Google Scholar]
  7. Lammie PJ, Reiss MD, Dimock KA, Streit TG, Roberts JM, Eberhard ML, 1998. Longitudinal analysis of the development of filarial infection and antifilarial immunity in a cohort of Haitian children. Am J Trop Med Hyg 59 : 217–221. [Google Scholar]
  8. Jungmann P, Figueredo-Silva J, Dreyer G, 1991. Bancroftian lymphadenopathy: a histopathologic study of fifty-eight cases from Northeastern Brazil. Am J Trop Med Hyg 45 : 325–331. [Google Scholar]
  9. Dreyer G, Figueredo-Silva J, Carvalho K, Amaral F, Ottesen EA, 2001. Lymphatic filariasis in children: adenopathy and its evolution in two young girls. Am J Trop Med Hyg 65 : 204–207. [Google Scholar]
  10. Amaral F, Dreyer G, Figueredo-Silva J, Noroes J, Cavalcanti A, Samico SC, Santos A, Coutinho A, 1994. Live adult worms detected by ultrasonography in human bancroftian filariasis. Am J Trop Med Hyg 50 : 753–757. [Google Scholar]
  11. Chaubal NG, Pradhan GM, Chaubal JN, Ramani SK, 2003. Dance of live adult filarial worms is a reliable sign of scrotal filarial infection. J Ultrasound Med 22 : 765–769. [Google Scholar]
  12. Dreyer G, Noroes J, Addiss D, Santos A, Medeiros Z, Figueredo-Silva J, 1999. Bancroftian filariasis in a paediatric population: an ultrasonographic study. Trans R Soc Trop Med Hyg 93 : 633–636. [Google Scholar]
  13. Dreyer G, Noroes J, Amaral F, Nen A, Medeiros Z, Coutinho A, Addiss D, 1995. Direct assessment of the adulticidal efficacy of a single dose of ivermectin in bancroftian filariasis. Trans R Soc Trop Med Hyg 89 : 441–443. [Google Scholar]
  14. Noroes J, Addiss D, Santos A, Medeiros Z, Coutinho A, Dreyer G, 1996. Ultrasonographic evidence of abnormal lymphatic vessels in young men with adult Wuchereria bancrofti infection in the scrotal area. J Urol 156 : 409–412. [Google Scholar]
  15. Dreyer G, Santos A, Noroes J, Rocha A, Addiss D, 1996. Amicrofilaremic carriers of adult Wuchereria bancrofti. Trans R Soc Trop Med Hyg 90 : 288–289. [Google Scholar]
  16. Suresh S, Kumaraswami V, Suresh I, Rajesh K, Suguna G, Vijayasekaran V, Ruckmani A, Rajamanickam MG, 1997. Ultrasonographic diagnosis of subclinical filariasis. J Ultrasound Med. 16 : 45–49. [Google Scholar]
  17. Noroes J, Addiss D, Amaral F, Coutinho A, Medeiros Z, Dreyer G, 1996. Occurrence of living adult Wuchereria bancrofti in the scrotal area of men with microfilaremia. Trans R Soc Trop Med Hyg 90 : 55–56. [Google Scholar]
  18. Dreyer G, Brandao AC, Amaral F, Medeiros Z, Addiss D, 1996. Detection by ultrasound of living adult Wuchereria bancrofti in the female breast. Mem Inst Oswaldo Cruz 91 : 95–96. [Google Scholar]
  19. Fox LM, Furness BW, Haser JK, Dardith D, Brissau JM, Milord MD, Lafontant J, Lammie PJ, Beach MJ, 2005. Tolerance and efficacy of combined diethylcarbamazine and albendazole for treatment of Wuchereria bancrofti and intestinal helminth infections in Haitian children. Am J Trop Med Hyg (in press).
  20. Eberhard ML, Lammie PJ, 1991. Laboratory diagnosis of filariasis. Clin Lab Med 11 : 977–1010. [Google Scholar]
  21. Dorlands Illustrated Medical Dictionary. 30th Edition. Elsevier, Philadelphia, PA. 98: 703–714. 2003.
  22. Gray’s Anatomic Basis of Medicine and Surgery. Churchill Livingston, UK, 38th Edition. 1995.
  23. Marshall WA, Tanner JM, 1968. Growth and physiologic development during adolescence. Annu Rev Med 19 : 283–300. [Google Scholar]
  24. Möller R, 1980. Arrangement and fine structure of lymphatic vessels in the human spermatic cord. Andrologia 12 : 564–576. [Google Scholar]
  25. Dondero TJ, Mullin SW, Balasingam S, 1972. Early clinical manifestations in filariasis due to Brugia malayi: observations on experimental infections in man. Southeast Asian J Trop Med Public Health 3 : 569–575. [Google Scholar]
  26. King BG, 1944. Early filariasis diagnosis and clinical findings: a report of 268 cases in American troops. Am J Trop Med 24 : 285–298. [Google Scholar]
  27. Bosshardt SC, Coleman SU, Thompson DL Jr, Klei TR, 1991. Altered adult worm location in young male jirds infected with Brugia pahangi. J Parasitol 77 : 631–633. [Google Scholar]
  28. Dreyer G, Amaral F, Noroes J, Medeiros Z, 1994. Ultrasonographic evidence for stability of adult worm location in bancroftian filariasis. Trans R Soc Trop Med Hyg 88 : 558. [Google Scholar]
  29. Dreyer G, Addiss D, Roberts J, Noroes J, 2002. Progression of lymphatic vessel dilatation in the presence of living adult Wuchereria bancrofti. Trans R Soc Trop Med Hyg 96 : 157–161. [Google Scholar]
  30. Mathieu E, Lammie PJ, Radday J, Montilus W, Beach MJ, Streit T, Wendt J, Addiss DG, 2004. Factors associated with participation in a campaign of mass treatment against lymphatic filariasis in Leogane, Haiti. Ann Trop Med Parasitol 98 : 703–714. [Google Scholar]
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  • Received : 28 May 2004
  • Accepted : 22 Aug 2004

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