Volume 72, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


O’nyong-nyong virus (ONNV) and chikungunya virus (CHIKV) are closely related alphaviruses that cause human disease in Africa and Asia. Like most alphaviruses, CHIKV is vectored by culicine mosquitoes. ONNV is considered unusual as it primarily infects anopheline mosquitoes; however, there are relatively few experimental data to support this. In this study, three strains of ONNV and one strain of CHIKV were evaluated in and mosquitoes and in four cell lines. As predicted, CHIKV was not infectious to , and we observed strain-variability for ONNV with respect to the ability of the virus to infect and . The species specificity was reflected by experiments using culicine and anopheline-derived cell lines.


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  • Received : 02 Sep 2004
  • Accepted : 29 Oct 2004

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