1921
Volume 72, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Thai patients with scrub typhus caused by the intracellular pathogen displayed elevated plasma concentrations of granzymes A and B, interferon-γ (IFN)-γ–inducible protein 10, and monokine induced by IFN-γ. These data suggest that activation of cytotoxic lymphocytes is part of the early host response to scrub typhus.

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2005-04-01
2017-11-18
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References

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  9. Spaeny-Dekking EH, Hanna WL, Wolbink AM, Wever PC, Kummer AJ, Swaak AJ, Middeldorp JM, Huisman HG, Froelich CJ, Hack CE, 1998. Extracellular granzymes A and B in humans: detection of native species during CTL responses in vitro and in vivo. J Immunol 160 : 3610–3616.
  10. Wever PC, Spaeny LH, van der Vliet HJ, Rentenaar RJ, Wolbink AM, Surachno J, Wertheim PM, Schellekens PT, Hack CE, ten Berge IJ, 1999. Expression of granzyme B during primary cytomegalovirus infection after renal transplantation. J Infect Dis 179 : 693–696.
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  • Received : 26 Aug 2004
  • Accepted : 03 Oct 2004

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