1921
Volume 72, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

an emerging pathogen bacterium, is the main causative agent of the cat scratch disease. While the first clinical descriptions were associated with immunosupressed patients, it is now more frequently observed in patients with normal immune status (endocarditis and bacteremia). Cats were found to be the only known reservoir of . In this paper, we report the results obtained in the first study made to investigate the prevalence of bacteremia and antibodies in domestic cats in Catalonia, Spain. Serum samples from 115 cats were tested for antibodies to by immunofluorescent antibody testing, and 29.6% had a titer ≥ 1:64. Seven strains were isolated using standard culture techniques and amplification by a polymerase chain reaction and subsequent sequencing was performed on the intergenic spacer region between the 16 and 23S ribosomal RNA genes. Of all factors concerning the studied bacteremia rate (age, sex, habitat, presence of antibodies, contact with animals, parasites), only the presence of antibodies to was statistically significant.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.2005.72.453
2005-04-01
2017-09-22
Loading full text...

Full text loading...

/deliver/fulltext/14761645/72/4/0720453.html?itemId=/content/journals/10.4269/ajtmh.2005.72.453&mimeType=html&fmt=ahah

References

  1. Brenner J, O’Connor S, Winkler H, Steigerwalt A, 1993. Proposals to unify the generan Bartonella and Rochalimaea, with descriptions of Bartonella quintana comb. nov., Bartonella vinsonii comb. nov., Bartonella henselae comb. nov., and Bartonella elizabethae comb. nov., and to remove the familia Bartonellaceae from the order Rickettsiales. Int J Syst Bacteriol 43 : 777–786.
  2. Birtles JR, Harrison TG, Saunders NA, Molyneux D, 1995. Proposals to unify the genera Grahamella and Bartonella, with descriptions of Bartonella talpae com. nov., Bartonella peromysci comb. nov., and three new species, Bartonella grahamii sp. nov., Bartonella taylorii sp. nov., and Bartonella doshiae sp. nov. Int J Syst Bacteriol 45 : 1–8.
  3. Kordick DL, Hilyard EJ, Hadfiel TL, Wilson KH, Steigerwalt AG, Brenner DJ, Breitschwerdt EB, 1997. Bartonella clarridgeiae, a new recognized zoonotic pathogen causing inoculation papules, fever, and lymphadenopathy (cat scratch disease). J Clin Microbiol 35 : 1813–1818.
  4. Heller R, Riegel P, Hansmann Y, Delacour G, Bermond D, Dehio C, Lamarque F, Monteil H, Chomel BB, Piémont Y, 1998. Bartonella tribocorum sp. nov., a new Bartonella species isolated from the blood of wild rats. Int J Syst Bacteriol 48 : 1333–1339.
  5. Kosoy M, Murray M, Gilmore RD, Bai Y, Gage KL, 2003. Bartonella strains from ground squirrels are identical to Bartonella washoensis isolated from a human patient. J Clin Microbiol 41 : 645–650.
  6. Droz A, Chi B, Horn E, Steigerwalt A, Whitney AM, Brenner DJ, 1999. Bartonella koehlerae sp. nov., isolated from cats. J Clin Microbiol 37 : 1117–1122.
  7. Heller R, Kubica M, Mariet P, Riegel P, Delacour G, Dehio C, Lamarque F, Kasten R, Boulouis HJ, Monteil H, Chomel BB, Piémont Y, 1999. Bartonella alsatica sp. nov., a new Bartonella species isolated from the blood of wild rabbits. Int J Syst Bacteriol 49 : 283–288.
  8. Bermond D, Heller R, Barrat F, Delacour G, Dehio C, Alliot A, Monteil H, Chomel B, Boulouis HJ, Piemont Y, 2000. Bartonella birtlesii sp. nov., isolated from small mammals (Apodemus spp.). Int J Syst Evol Microbiol 50 : 1973–1979.
  9. Dehio C, Lanz C, Pohl R, Behrens P, Bermond D, Piemont Y, Pelz K, Sander A, 2001. Bartonella schoenbuchii sp. nov., isolated from the blood of wild roe deer. Int J Syst Evol Microbiol 51 : 1557–1565.
  10. Bermond D, Boulouis HJ, Heller R, van Laere G, Monteil H, Chomel BB, Sander A, Dehio C, Piemont Y, 2002. Bartonella bovis. sp. nov. and Bartonella capreoli sp. nov., isolated from European ruminants. Int J Syst Evol Microbiol 52 : 383–390.
  11. Alsmark CM, Frank AC, Karlberg EO, Legault BA, Ardell DH, Canback B, Eriksson AS, Naslund AK, Handley SA, Huvet M, La Scola B, Holmberg M, Andersson SG, 2004. The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae. Proc Natl Acad Sci USA 101 : 9716–9721.
  12. Chomel BB, Boulouis HJ, Breitschwerdt EB, 2004. Cat scratch disease and other zoonotic Bartonella infections. J Am Vet Med Assoc 224 : 1270–1279.
  13. Comer JA, Paddock CD, Childs JE, 2001. Urban zoonoses caused by Bartonella, Coxiella, Ehrlichia, and Rickettsia species. Vector Borne Zoonotic Dis 1 : 91–118.
  14. Johnson G, Ayers M, McClure SC, Richardson SE, Tellier R, 2003. Detection and identification of Bartonella species pathogenic for humans by PCR amplification targeting the riboflavin synthase gene (ribC). J Clin Microbiol 41 : 1069–1072.
  15. Kerkhoff FT, Bermans AMC, van der Zee A, Rothova A, 1999. Demonstration of Bartonella grahamii DNA in ocular fluids of a patient with neuroretinitis. J Clin Microbiol 37 : 4034–4038.
  16. Mansueto P, Di Lorenzo G, Rizzo M, Mazzola G, Affronti M, Battista Rini G, Mansueto S, 2003. Bartonellosis. Recenti Prog Med 94 : 177–185.
  17. Avidor B, Graidy M, Efrat G, Leibowitz C, Shapira G, Schattner A, Zimhony O, Giladi M, 2004. Bartonella koehlerae, a new cat-associated agent of culture-negative human endocarditis. J Clin Microbiol 42 : 3462–3468.
  18. Aguirrebengoa K, Benito JR, Montejo M, Bereciartua E, Perez-Irezabal J, Gonzalez-Zarate P, 1999. Cat-scratch disease: series of 14 cases. The diagnostic usefulness of serology. Enferm Infecc Microbiol Clin 17 : 15–18.
  19. Chomel BB, 1996. Cat-scratch disease and bacillary angiomatosis. Rev Sci Tech 15 : 1061–1073.
  20. Brouqui P, Lascola B, Roux V, Raoult D, 1999. Chronic Bartonella quintana bacteremia in homeless patients. N Engl J Med 340 : 184–189.
  21. Raoult D, Fournier PE, Drancourt M, Marrie J, Etienne J, Cosserat J, Cacoub P, Poinsignon Y, Leclercq P, Sefton AM, 1996. Diagnosis of 22 new cases of Bartonella endocarditis. Ann Intern Med 125 : 646–652.
  22. Chomel BB, Abbott JG, Kasten RW, Floyd-Hawkins KA, Kass PH, Glasser CA, Pederson NC, Koehler JE, 1995. Bartonella henselae prevalence in domestic cats in California: risk factors and association between bacteremia and antibody titers. J Clin Microbiol 33 : 2445–2450.
  23. Chomel BB, Kasten RW, Floyd-Hawkins KA, Chi B, Yamamoto K, Roberts-Wilson J, Gurfield A, Abbott R, Pedersen NC, Koehler JC, 1996. Experimental transmission of Bartonella henselae by the cat flea. J Clin Microbiol 34 : 1952–1956.
  24. Nasirudee AMA, Thong ML, 1999. Prevalence of Bartonella henselae immunoglobulin G antibodies in Singapurean cats. Pediatr Infect Dis J 18 : 276–278.
  25. Glaus T, Hofmann-Lehmann R, Greene C, Glaus B, Wolfensberger C, Lutz H, 1997. Seroprevalence of Bartonella henselae infection and correlation with disease status in cats in Switzerland. J Clin Microbiol 35 : 2883–2885.
  26. Bergh K, Bevanger L, Hanssen L, Loseth K, 2002. Low prevalence of Bartonella henselae infections in Norwegian domestic and feral cats. APMIS 100 : 309–314.
  27. Heller R, Artois M, Xemar V, Briel D, Gehin H, Jaulhac B, Montiel H, Piemont Y, 1997. Prevalence of Bartonella henselae and Bartonella clarridgeiae in stray cats. J Clin Microbiol 35 : 1327–1331.
  28. Chomel BB, Carlos ET, Kasten RW, Yamamoto K, Chang CC, Carlos RS, Abenes MV, Pajares CM, 1999. Bartonella henselae and Bartonella clarridgeiae infection in domestic cats from the Philippines. Am J Trop Med Hyg 60 : 593–597.
  29. Jensen WA, Fall MZ, Rooney J, Kordick DL, Breitschwerdt EB, 2000. Rapid identification and differentiation of Bartonella species using a single-step PCR assay. J Clin Microbiol 38 : 1717–1722.
  30. Regnery RL, Olson JG, Perkins BA, Bibb W, 1992. Serological response to “Rochalimaea henselae” antigen in suspected cat-scratch disease. Lancet 339 : 1443–1445.
  31. Zbinden R, Michael N, Sekulovski A, Graevenitz A, Nadal D, 1997. Evaluation of commercial slides for detection of immunoglobulin G against Bartonella henselae by indirect immunofluorescence. Eur J Clin Microbiol Infect Dis 16 : 648–652.
  32. Breitschwerdt E, Kordick DL, 2000. Bartonella infection in animals: carriership, reservoir potential, pathogenicity and zoonotic potential for human infection. Clin Microbiol Rev 13 : 428–438.
  33. Koehler JE, Glaser CA, Tappero JW, 1994. Rochalimaea henselae infection. A new zoonosis with domestic cat as reservoir. JAMA 271 : 531–535.
  34. Seubert A, Schulein R, Dehio C, 2002. Bacterial persistence within erythrocytes: a unique pathogenic strategy of Bartonella spp. Int J Med Microbiol 291 : 555–560.
  35. Arvand M, Klose AJ, Schwartz-Porsche D, Hahn H, Wendt C, 2001. Genetic variability and prevalence of Bartonella henselae in cats in Berlin, Germany, and analysis of its genetics relatedness to a strain from Berlin that is pathogenic for humans. J Clin Microbiol 39 : 743–746.
  36. Sander A, Bühler C, Pelz K, Cramm E, Bredt W, 1997. Detection and identification of two Bartonella henselae variants in domestic cats in Germany. J Clin Microbiol 35 : 584–587.
  37. Marston E, Finkel B, Regnery R, Winoto I, Graham R, Wignal S, Simanjuntak G, Olson J, 1999. Prevalence of Bartonella henselae and Bartonella clarridgeiae in an urban Indonesian cat population. Clin Diagn Lab Immunol 6: 41–44.
  38. Gurfield AN, Boulouis HJ, Chomel BB, Heller R, Kasten RW, Yamamoto K, Piemont Y, 1997. Coinfection with Bartonella clarridgeiae and Bartonella henselae and with different Bartonella henselae strains in domestic cats. J Clin Microbiol 35 : 2120–2123.
  39. Bergmans AMC, Jong CMA, Amerongen G, Schot CS, Schouls LM, 1997. Prevalence of Bartonella species in domestic cats in the Netherlands. J Clin Microbiol 35 : 256–261.
  40. Piémont Y, Bermond D, 2001. Infections caused by Bartonella spp. Ann Biol Clin (Paris) 59 : 593–604.
  41. de Souza Zanutto M, Mamizuka EM, Raiz R Jr., de Lima TM, Diogo CL, Okay TS, Hagiwara MK, 2001. Experimental infection and horizontal transmission of Bartonella henselae in domestic cats. Rev Inst Med Trop Sao Paulo 43 : 257–261.
  42. Fabbi M, de Giuli L, Tranquillo M, Bragoni R, Casiraghi M, Genchi C, 2004. Prevalence of Bartonella henselae in Italian stray cats: evaluation of serology to assess the risk of transmission of Bartonella to humans. J Clin Microbiol 42 : 264–268.
  43. Hjelm E, McGill S, Blomqvist G, 2002. Prevalence of antibodies to Bartonella henselae, B. elizabethae and B. quintana in Swedish domestic cats. Scand J Dis 34 : 192–196.
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.2005.72.453
Loading
/content/journals/10.4269/ajtmh.2005.72.453
Loading

Data & Media loading...

  • Received : 09 Mar 2004
  • Accepted : 05 Nov 2004

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error