Volume 72, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


In August 2002, two cases of hantavirus pulmonary syndrome (HPS) were confirmed in Mineros and Concepción, within the Santa Cruz Department of Bolivia. Extensive alteration of the native ecosystem, from dense forest to pasture or sugarcane, had occurred in both regions. An ecologic assessment of reservoir species associated with the human disease identified a single hantavirus antibody-positive from Mineros and three hantavirus antibody-positive from Concepción. In Mineros, the virus from the was 90% similar to sequences published for Río Mamoré virus. Viral nucleotide sequences from two were 87–88% similar to the sequence of Laguna Negra virus. The viral sequence from the was 99% identical to viral sequences obtained from the HPS patient in this area, implicating as the host and Laguna Negra virus as the agent responsible for the HPS case near Concepción.


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  • Received : 24 Nov 2003
  • Accepted : 22 Jan 2004

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