1921
Volume 71, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

In a randomized open study, we compared the efficacy of a single dose of oral ivermectin (200 μg/kg) and oral albendazole (400 mg/day for 21 days) for the treatment of cutaneous gnathostomiasis. Thirty-one patients were randomly assigned to receive ivermectin (n = 17) or albendazole (n = 14). Thirteen of 17 patients who received ivermectin responded, 3 relapsed, and 1 was unresponsive (cure rate = 76%). Thirteen of 14 patients who received albendazole responded very well and did not relapse. Only one patient was unresponsive (cure rate = 92%; > 0.05). No major side effects were observed in both groups. We concluded that a single dose of ivermectin (200 μg/kg) is less effective than albendazole (400 mg/day for 21 days) for treatment of cutaneous gnathostomiasis, but there was no statistically significant difference ( > 0.05).

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2004-11-01
2017-11-21
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  • Received : 17 Feb 2004
  • Accepted : 11 May 2004

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