1921
Volume 71, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

A retrospective cohort analysis was conducted in Kazakhstan to define modifiable risk factors during seven outbreaks of human anthrax. Fifty-three cases and 255 non-ill persons with an epidemiologic link to an infected animal were enrolled. Cases were 58% male and had a median age of 35 years (range = 5–71). Nearly all cases had cutaneous disease (96%). Two patients (4%) were diagnosed with gastrointestinal disease. Although all cases had some contact with an infected animal other than consumption, in multivariable analysis the act of butchering an animal (relative risk [RR] = 3.6, 95% confidence interval [CI] = 1.5–9.6) and the presence of visible cuts on the hands were associated with anthrax (RR = 3.0, 95% CI = 0.9–9.6). Contact with infected livestock, in particular butchering, is associated with developing anthrax. The risk may be exacerbated by the presence of cuts on the hands at the time of contact with the animal or animal products.

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2004-07-01
2017-11-25
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References

  1. Brachman PS, 1989. Anthrax. Hoeprich P, ed. Infectious Diseases. Fourth edition. New York: Harper and Rowe, 1007–1013.
  2. Christie AB, 1973. The clinical aspects of anthrax. Postgrad Med J 49 : 565–570.
  3. Turnbull PC, Hugh-Jones ME, Cosivi O, 1999. World Health Organization activities on anthrax surveillance and control. J Appl Microbiol 87 : 318–320.
  4. Johnson-Winegar A, 1984. Comparison of enzyme-linked immunosorbent and indirect hemagglutination assays for determining anthrax antibodies. J Clin Microbiol 20 : 357–361.
  5. Davis CE, Hyde JE, Bangdiwala SI, Nelson JJ, 1986. An example of dependencies among variables in a conditional logistic regression. Moolgavkar SH, Prentice RL, eds. Modern Statistical Methods in Chronic Disease Epidemiology. New York: John Wiley & Sons, Inc., 140–147.
  6. McKendrick DR, 1980. Anthrax and its transmission to humans. Cent Afr J Med 26 : 126–129.
  7. James DG, 1976. Epidemiology of anthrax. J Antimicrob Chemother 2 : 319–320.
  8. Hugh-Jones M, 1999. 1996–97 Global anthrax report. J Appl Microbiol 87 : 189–191.
  9. Lew D, 1995. Bacillus anthracis (Anthrax). Mandell GL, Bennett JE, Dolin R, eds. Principles and Practices of Infectious Disease. New York: Churchill-Livingstone; 1885–1889.
  10. Anonymous, 1918. Precautions for preventing danger of infection from anthrax in the manipulation of wool, goat hair, and camel hair. Rep Depart Committee Anthrax 3 : 116.
  11. Lewis-Jones MS, Baxby D, Cefai C, Hart CA, 1993. Cowpox can mimic anthrax. Br J Dermatol 129 : 625–627.
  12. Harrison LH, Ezzell JW, Abshire TG, Kidd S, Kaufmann AF, 1989. Evaluation of serologic tests for diagnosis of anthrax after an outbreak of cutaneous anthrax in Paraguay. J Infect Dis 160 : 706–710.
  13. Turnbull PCB, Kramer JM, 2002. Bacillus. Murray PR, Baron EJ, Pfaller MA, Tenover FC, Yolken RH, eds. Manual of Clinical Microbiology. Sixth edition. Washington, DC: American Society for Microbiology Press, 349–356.
  14. Bharathmoorthy, Chakravarthy I, Swaminathan RP, Das AK, Malini G, Rebakanungo, Rao S, 1992. Haemorrhagic meningitis due to Bacillus anthrax. J Assoc Physicians India 40 : 134–135.
  15. Kanafani ZA, Ghossain A, Sharara AI, Hatem JM, Kanj SS, 2003. Endemic gastrointestinal anthrax in 1960s Lebanon: clinical manifestations and surgical findings. Emerg Infect Dis 9 : 520–525.
  16. Jena GP, 1980. Intestinal anthrax in man: a case report. Cent Afr J Med 26 : 253–254.
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  • Received : 12 Nov 2003
  • Accepted : 04 Jan 2004

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