Volume 70, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


This study examines hematologic profiles of persons with acute or infection in Maesod on Thailand’s western border with Myanmar compared with febrile, non-parasitemic persons also reporting to malaria clinics. Nine hundred seventy-nine subjects were malaria-negative, 414 were infected with , and 646 were infected with Persons with patent parasitemia tended to have significantly lower white blood cell, red blood cell, platelet, and hemoglobin levels than those who were malaria-negative. For the first time, a parallel trend in thrombocytopenia with parasitemia was found to be associated with both and infection. Using logistic regression, persons with platelet counts < 150,000/μL were 12–15 times more likely to have malaria than persons with platelet counts ≥ 150,000/μL. This study supplements previous literature on the hematologic effects of malaria and helps define those alterations for a semi-immune population. Thrombocytopenia is identified as a key indicator of malaria in these febrile patients.


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  • Received : 11 Jul 2003
  • Accepted : 20 Sep 2003

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