1921
Volume 70, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

A retrospective examination was made of archival data collected between 1940 and 1963 on the infection of mosquitoes with the St. Elizabeth strain of . Patients were undergoing malariatherapy for the treatment of neurosyphilis. A total of 845 lots of mosquitoes were fed during primary infections and 76 during secondary infections. Average percentage infection during the primary infection was 56.55% versus 49.83% during the secondary infection. There appeared to be no relationship between microgametocye density, asexual parasite count, and percentage infection. However, very high fevers appear to have a significant effect on infection rates. Persons with fever ≥ 105°F showed the lowest rates of infectivity regardless of parasitemia; persons with moderate (101–104.8°F) fever produced somewhat higher rates, and persons with no fever had the highest levels of infection at all parasitemia levels greater than 1,500/μL

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2004-06-01
2017-11-21
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References

  1. Collins WE, Jeffery GM, 1999. A retrospective examination of sporozoite- and trophozoite-induced infections with Plasmodium falciparum: development of parasitologic and clinical immunity during primary infection. Am J Trop Med Hyg 61 (Suppl): 4–19.
  2. Collins WE, Jeffery GM, 1999. A retrospective examination of secondary sporozoite- and trophozoite-induced infections with Plasmodium falciparum: development of parasitologic and clinical immunity following secondary infection. Am J Trop Med Hyg 61 (Suppl): 20–35.
  3. Collins WE, Jeffery GM, 1999. A retrospective examination of secondary sporozoite- and trophozoite-induced infections with Plasmodium falciparum in patients previously infected with heterologous species of Plasmodium: effect on development of parasitologic and clinical immunity. Am J Trop Med Hyg 61 (Suppl): 36–43.
  4. Collins WE, Jeffery GM, 1999. A retrospective examination of patterns of recrudescence in patients infected with Plasmodium falciparum. Am J Trop Med Hyg 61 (Suppl): 44–48.
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  • Received : 26 Nov 2003
  • Accepted : 10 Mar 2004

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