Volume 70, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


This study was designed to examine stool specimens of irritable bowel syndrome (IBS) patients for , a common intestinal parasite. One hundred fifty patients were enrolled, 95 IBS cases and 55 controls. These patients provided a medical history, and underwent physical and laboratory evaluations that included stool microscopy and culture for and colonoscopy. The 95 cases (51 males and 44 females) had a mean ± SD age of 37.8 ± 13.2 years. Stool microscopy was positive for in 32% (30 of 95) of the cases and 7% (4 of 55) of the controls ( = 0.001). Stool culture was positive in 46% (44 of 95) of the cases and 7% (4 of 55) of the controls ( < 0.001). Stool culture for in IBS was more sensitive than microscopy ( < 0.001). was frequently demonstrated in the stool samples of IBS patients; however, its significance in IBS still needs to be investigated. Stool culture has a higher positive yield for than stool microscopy.


Article metrics loading...

The graphs shown below represent data from March 2017
Loading full text...

Full text loading...



  1. Zierdt CH, 1988. Blastocystis hominis, a long misunderstood intestinal pathogen. Parasitol Today 4 : 15–17. [Google Scholar]
  2. Zaman V, 1996. Blastocystis hominis. Weatherall DJ, Ledingham JGG, Warrell D, eds. Oxford Textbook of Medicine. Third Edition. Oxford: Oxford University Press, 887.
  3. Zaman V, Khan K, 1994. A comparison of direct microscopy with culture for the diagnosis of Blastocystis hominis. Southeast Asian J Trop Med Hyg Public Health 25 : 792–793. [Google Scholar]
  4. Zierdt CH, 1991. Blastocystis hominis past and future. Microbiol Review 4 : 61–79. [Google Scholar]
  5. Hussain R, Jafri W, Zuberi S, Baqai R, Abrar N, Ahmed A, Zaman V, 1997. Significantly increased IgG2 subclass antibody levels to Blastocystis homonis in patients with Irritable bowel syndrome. Am J Trop Med Hyg 56 : 301–306. [Google Scholar]
  6. Ashford RW, Atkinson EA, 1992. Epidemiology of Blastocystis hominis in Papua New Guinea: age prevalence and associations with other parasites. Ann Trop Med Parasitol 86 : 129–136. [Google Scholar]
  7. Thompson WG, Longstreth GF, Drossman DA, Heaton KW, Irvine EJ, Muller-Lissner SA, 1999. Functional bowel disorders and functional abdominal pain. Gut 45 (Suppl 2): 1143–1147. [Google Scholar]
  8. Icci N, Toma P, Furlani M, Caselli M, Guillini S, 1984. Blastocystis hominis: a neglected cause of diarrhea? Lancet i : 966. [Google Scholar]
  9. Llibre JM, Tor J, Manterola JM, Carbonell C, Foz M, 1989. Blastocystis hominis chronic diarrhea in AIDS patients (letter). Lancet i : 221. [Google Scholar]
  10. Taamasri P, Mungthin M, Rangsin R, Tongupprakarn B, Areekul W, Leelayoova S, 2000. Transmission of intestinal blastocystosis related to the quality of drinking water. Southeast Asian J Trop Med Public Health 31 : 112–117. [Google Scholar]
  11. Singh M, Suresh K, Ho LC, Ng GC, Yap EH, 1995. Elucidation of the life cycle of the intestinal protozoan Blastocystis hominis. Parasitol Res 81 : 446–450. [Google Scholar]
  12. Vdovenko AA, 2000. Blastocystis hominis: origin and significance of vacuolar and granular forms. Parasitol Res 86 : 8–10. [Google Scholar]
  13. Nimri L, Batchoun R, 1994. Intestinal colonization of symptomatic and asymptomatic school children with Blastocystis hominis. J Clin Microbiol 32 : 2865–2866. [Google Scholar]
  14. Kain KC, Noble MA, Freeman HJ, Barteluk RL, 1987. Epidemiology and clinical features associated with Blastocystis hominis infection. Diagn Microbiol Infect Dis 8 : 235–244. [Google Scholar]
  15. Kain KC, Ravdin JI, 1995. Galactose-specific adhesion mechanisms of Entamoeba histolytica: model for study of enteric pathogens. Methods Enzymol 253 : 424–439. [Google Scholar]
  16. Thompson RCA, Reynoldson JA, Mendis AHW, 1993. Giardia and giardiasis. Adv Parasitol 32 : 71–160. [Google Scholar]
  17. Walderich B, Bernauer S, Renner M, Knobloch J, Burchard GD, 1998. Cytopathic effects of Blastocystis hominis on Chinese hamster ovary (CHO) and adenocarcinoma HT 29 cell cultures. Trop Med Int Health 3 : 385–390. [Google Scholar]
  18. Carrascosa M, Martinez J, Perez-Castrillon JL, 1996. Hemorrhagic proctosigmoiditis and Blastocystis hominis infection. Ann Intern Med 15 : 278–279. [Google Scholar]
  19. Ghosh K, Ayyaril M, Nirmala V, 1998. Acute GVHD involving the gastrointestinal tract and infestation with Blastocystis hominis in a patient with chronic myeloid leukaemia following allogeneic bone marrow transplantation. Bone Marrow Transplant 22 : 1115–1117. [Google Scholar]
  20. Phillips BP, Zierdt CH, 1976. Pathogenic potential in human patients and in gnotobiotes. Exp Parasitol 39 : 358–364. [Google Scholar]
  21. Collins SM, 1994. Irritable bowel syndrome could be an inflammatory disorder. Eur J Gastroenterol Hepatol 6 : 478–483. [Google Scholar]

Data & Media loading...

  • Received : 02 Jul 2003
  • Accepted : 13 Jan 2004

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error