1921
Volume 70, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

The predominant sand fly species collected inside houses in Kfar Adumim, an Israeli village in the Judean Desert that is a focus of cutaneous leishmaniasis, was which was also caught attempting to bite humans. , which is rarely seen inside houses, constituted the predominant sand fly species in caves near the village. isolates from and humans typed as . Sand fly and human isolates produced similar small nodular cutaneous lesions in hamsters. Isolates produced excreted factor (EF) of subserotypes A or AB, characteristic of and reacted with -specific monoclonal antibodies. Isoenzyme analysis consigned the strains to the zymodemes MON-137 and MON-275. Molecular genetic analyses confirmed the strains were and intraspecific microheterogeneity was observed. Genomic fingerprinting using a mini-satellite probe separated the strains into two clusters that were not entirely congruent with geographic distribution. These results support the heterogeneous nature of and incriminate as its vector in this Judean Desert focus.

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  • Received : 02 Jul 2003
  • Accepted : 09 Oct 2003

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