1921
Volume 70, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

We conducted a school-based assessment of the geographic distribution of infection in Leogane Commune, Haiti, using the immunochromatographic test. In multivariate analyses performed using generalized linear mixed models, children attending schools in the foothills and plains were 3.95 (95% confidence interval [CI] = 1.28–12.23) and 23.56 (95% CI = 8.99–61.79) times as likely to be infected, respectively, as children attending mountain schools. Infection prevalence decreased with increasing altitude, but some local foci of infection were detected at higher altitudes. Higher school tuition, a marker of socioeconomic status (SES), was not associated with decreased infection prevalence. Our results indicate that although the force of infection in Leogane Commune is greatest below 70 meters above sea level, higher altitude communities are not exempt from infection. Lymphatic filariasis (LF) elimination programs should consider extending infection mapping activities to presumed non-LF altitudes. In addition, higher SES does not confer protection against infection.

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2004-03-01
2017-09-21
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References

  1. Michael E, Bundy DAP, Grenfell BT, 1996. Re-assessing the global prevalence and distribution of lymphatic filariasis. Parasitology 112 : 409–428.
  2. World Health Organization, 1997. World Health Assembly Resolution 50.29. Geneva: World Health Organization.
  3. Ramzy RM, Hafez ON, Gad AM, Faris R, Harb M, Buck AA, Weil GJ, 1994. Efficient assessment of filariasis endemicity by screening for filarial antigenaemia in a sentinel population. Trans R Soc Trop Med Hyg 88 : 41–44.
  4. World Health Organization, 1998. Research of Rapid Geographic Assessment of Bancroftian Filariasis. Geneva: World Health Organization. TDR/TDF/COMDT/98.2).
  5. World Health Organization, 1999. Report of a WHO Informal Consulation on Epidemiologic Approaches to Lymphatic Filariasis Elimination: Initial Assessment, Monitoring and Certification. Geneva: World Health Organization. WHO/FIL/99.195.
  6. World Health Organization, 1999. Guidelines for Certifying Lymphatic Filariasis Elimination (Including Discussion of Critical Issues and Rationale). Geneva; World Health Organization. WHO/FIL/99.197.
  7. Breslow NE, Clayton DG, 1993. Approximate inference in generalized linear mixed models. J Am Stat Assoc 88 : 9–25.
  8. Agresti A, Booth JG, Hobert JP, Caffo B, 2000. Random-effects modeling of categorical response data. Sociol Methodol 30 : 27–80.
  9. Littell RC, Milliken GA, Stroup WW, Wolfinger RD, 1996. SAS ® System for Mixed Models. Cary, NC: SAS Institute, Inc., 423–460, 491–495.
  10. Onapa AW, Simonesen PE, Pedersen EM, Okello DO, 2001. Lymphatic filariasis in Uganda: baseline investigations in Lira, Soroti and Katakwi districts. Trans R Soc Trop Med Hyg 95 : 161–167.
  11. Sherchand JB, Obsomer V, Thakur GD, Hommel M, 2003. Mapping of lymphatic filariasis in Nepal. Filaria J 2 : 7. (http://www.filariajournal.com/content/2/1/7).
  12. Molyneux DH, Zagaria N, 2002. Lymphatic filariasis elimination: progress in global programme development. Ann Trop Med Parasitol 96 : S15–S40.
  13. Evans DB, Gelband H, Vlassoff C, 1993. Social and economic factors and the control of lymphatic filariasis: a review. Acta Trop 53 : 1–26.
  14. Hunter JM, 1992. Elephantiasis: a disease of development in northeast Ghana. Soc Sci Med 35 : 627–649.
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  • Received : 22 Sep 2003
  • Accepted : 25 Nov 2003

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