1921
Volume 69, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Microscopic detection of species has been the reference standard for the diagnosis of malaria for more than a century. However, maintaining a sufficient level of expertise in microscopic diagnosis can be challenging, particularly in non-endemic countries. The objective of this study was to compare a new rapid malaria diagnostic device (NOW ICT Malaria Test; Binax, Inc., Portland, ME) to polymerase chain reaction (PCR) and expert microscopy for the diagnosis of malaria in 256 febrile returned travelers. Compared with PCR, the NOW ICT test showed a sensitivity of 94% for the detection of malaria (96% for pure infection) and 84% for non- infections (87% for pure infections and 62% for pure and infections), with an overall specificity of 99%. The Binax NOW ICT may represent a useful adjunct for the diagnosis of and malaria in febrile returned travelers.

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2003-12-01
2017-10-24
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  • Received : 16 Jul 2003
  • Accepted : 05 Sep 2003

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