Volume 69, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


Drug-resistant is present in Vietnam. We assessed the sensitivity of to halofantrine in two villages in the southern part of central Vietnam. Halofantrine (8 mg/kg × 3 doses) was administered to 37 patients with either (n = 32) or mixed malaria (n = 5). End points were parasite sensitivity or resistance (RI/RII/RIII) determined by parasite clearance, persistence, or recurrence during 28 days of follow-up. By day 28, 31 (93.9%) of 33 (95% confidence interval = 79.8–99.2%) patients were sensitive. Two patients had recurrent parasitemia on days 14 and 21. Halofantrine effectively treated uncomplicated malaria in these Vietnamese patients.


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  • Received : 17 Sep 2002
  • Accepted : 26 Apr 2003
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