Volume 69, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


B cell-deficient C57Bl/6 (μMT) mice were resistant to after both primary and secondary parasite challenge. However, unlike in wild-type mice, secondary infection in μMT mice was not accompanied by a marked delayed type hypersensitivity-like response, and interferon-γ (IFN-γ) levels were approximately half of those in wild-type mice. These results suggest that B cells are involved in IFN-γ production and the pathology of secondary infection.


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  • Received : 10 Jul 2003
  • Accepted : 22 Aug 2003

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