Volume 69, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


The presence of two oncosphere antigens OAs of 22.5 and 31.3 kD in whole and excretory/secretory (ES) OA preparations of both and or in antigen preparations from metacestodes or immature tapeworms was assessed. This included an evaluation of whether antibodies to other cestodes cross-reacted to these OAs. The OAs were present in whole oncosphere extract and E/S antigens of , but were not present in other stages (immature tapeworm or metacestode) or in OAs of . The majority (95%) of tapeworm carriers had antibodies to these OAs, while only 20% of active neurocysticercosis cases were positive. No antibodies to the OAs were found in healthy controls, subjects infected with , patients with hydatid disease, tapeworm carriers, hamsters infected with immature tapeworms, or dogs infected with . The OAs are stage and species specific to and antibodies to OAs are usually present in tapeworm carriers.


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  • Received : 27 Feb 2003
  • Accepted : 10 Jul 2003

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