Volume 69, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


Strongyloidiasis is a parasitosis characterized by persistent infection before dissemination and the development of potentially fatal disease. Since diagnosis is difficult, knowledge of the prevalence and geographic distribution of the disease is of practical importance. A study was made of infection in a random and representative sample of farm workers in a tourist region in Spain based on the detection of larvae of triple stool samples. The prevalence of infection was 12.4% (95% confidence interval [CI] = 8.4–16.4). None of the 26 clinical or epidemiologic variables analyzed were found to be predictive of infection. Only eosinophilia (> 400 eosinophils/mm ) was significantly greater among the infected individuals (odds ratio = 73.4, 95% CI = 16.3–327.0), with a sensitivity of 93.5% and a specificity of 93.1%. A screening program is proposed to detect eosinophilia, to provide treatment without stool examinations, and thus afford a cost-effective policy for preventing the development of severe forms of the disease among specific risk groups where the prevalence of other parasitoses is low.


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  1. Liu LX, Weller PF, 1993. Strongyloidiasis and other intestinal nematode infections. Infect Dis Clin North Am 7 : 655–682.
  2. Siddiqui AA, Berck S, 2001. Diagnosis of Strongyloides stercoralis infection. Clin Infect Dis 33 : 1040–1047.
  3. Uparanukraw P, Phongsri S, Morakote N, 1999. Fluctuations of larval excretion in Strongyloides stercoralis infection. Am J Trop Med Hyg 60 : 967–973.
  4. Zaha O, Hirata T, Kinjo F, Saito A, 2000. Strongyloidiasis-Progress in diagnosis and treatment. Intern Med 39 : 695–700.
  5. Genta RM, 1989. Global prevalence of strongyloidiasis: critical review with epidemiologic insights into the prevention of disseminated disease. Rev Infect Dis 11 : 755–767.
  6. Batista N, Davila MF, Gijón H, Perez MA, 1992. Estrongiloidiasis en un paciente con el síndrome de inmunodeficiencia adquirida. Enferm Infecc Microbiol Clin 10 : 431–432.
  7. Gomez J, Plaza V, Muñoz C, Franquet T, 1997. Hiperinfección-por Strongyloides stercoralis y otros patógenos en un paciente con enfermedad obstructiva crónica corticodependiente. Med Clin (Barc) 109 : 609.
  8. Cremades-Romero MJ, Igual-Adell R, Ricart-Olmos C, Estelles-Piera F, Pastor-Guzman A, Menendez-Villanueva R, 1997. Infección por Strongyloides stercoralis en la comarca de la safor (Comunidad Valenciana). Med Clin (Barc) 109 : 212–215.
  9. Rodriguez-Calabuig D, Oltra-Alcaraz C, Igual-Adell R, Parra-Godoy F, Martinez-Sanchez J, Angel-Rodenas C, 1998. Treinta casos de estrongiloidiasis en un centro de atención primaria:características y posibles complicaciones. Aten Primaria 31 : 271–274.
  10. Román-Sánchez P., Pastor-Guzmán A., Moreno-Guillen S., Igual-Adell R., Martin-Estruch A., Navarro-Gonzalo I, 2001. Endemic strongyloidiasis on the Spanish Mediterranean coast. QJM 94 : 357–363.
  11. Arakaki T, Iwanaga M, Kinjo F, Saito A, Asato R, Ikeshiro T, 1990. Efficacy of agar-plate culture in detection of Strongyloides stercoralis infection. J Parasitol 76 : 425–428.
  12. Sorozcan W, 1994. Strongyloides stercoralis intestinal roundworm. II. Geographic distribution. Wiad Parazytol 40 : 115–126.
  13. Huminer D, Symon K, Groskpof I, Pietrushka D, Kremer I, Schantz PM, Pitlik SD, 1992. Seroepidemiologic study of toxocariasis and strongyloidiasis in institutionalized mentally retarded adults. Am J Trop Med Hyg 46 : 278–281.
  14. Burken MI, Kittur SD, Peterson WC, 1995. Strongyloides stercoralis infection in a chronically institutionalized patient with schizophrenia and dementia. Clin Infect Dis 21 : 1047.
  15. Walzer PD, Milder JE, Banwell JG, Kilgore G, Klein M, Parker R, 1982. Epidemiologic features of Strongyloides stercoralis infection in an endemic area of the United States. Am J Trop Med Hyg 31 : 313–319.
  16. Pelletier L, Baker C, Gam A, Nutman T, Neva F, 1988. Diagnosis and evaluation of treatment of chronic strongyloidiasis in ex-prisoners of war. J Infect Dis 157 : 573–576.
  17. Scaglia M, Brustia R, Gatti S, Bernuzzi AM, Strosselli M, Malfitano A, Capelli D, 1984. Autochthonus strongyloidiasis in Italy: an epidemiological and clinical review of 150 cases. Bull Soc Pathol Exot Filiales 77 : 328–332.
  18. Doury P, 1993. Autochthonous anguilluliasis in France. Bull Soc Pathol Exot 86 : 116–119.
  19. Panaitescu D, Capraru T, Bugarin V, 1995. Study of the incidence of intestinal and systemic parasitoses in a group of children with handicaps. Roum Arch Microbiol Immunol 54 : 65–74.
  20. Ciesielski SD, Seed JR, Ortiz JC, Metts J, 1992. Intestinal parasites among North Carolina migrant farm workers. Am J Public Health 82 : 1258–1262.
  21. Gbakima AA., Sahr F, 1995. Intestinal parasitic infections among rural farming communities in eastern Sierra Leone. Afr J Med Med Sci 24 : 195–200.
  22. Agi PI, 1997. Comparative helminth infections of man in two rural communities of the Niger Delta, Nigeria. West Afr J Med 16 : 232–236.
  23. Kobayashi J, Hasegawa H, Soares EC, Toma H, Dacal AR, Brito MC, 1996. Studies on prevalence of Strongyloides infection in Holambra and Maceió, Brazil, by the agar plate faecal culture method. Rev Inst Med Trop Sao Paulo 38 : 279–284.
  24. Kobayashi J, Hasegawa H, Forli AA, Nishimura NF, Yamanaka A, Shimabukuro T, 1995. Prevalence of intestinal parasitic infection in five farms in Holambra, Sao Paulo, Brazil. Rev Inst Med Trop Sao Paulo 37 : 13–18.
  25. Bangs MJ., Purnomo, Andersen EM, Anthony RL, 1996. Intestinal parasites of humans in highland community of Irian Jaya, Indonesia. Am Trop Med Parasitol 90 : 49–53.
  26. Chai JY, Hongvanthong B, 1998. A small-scale survey of intestinal helminthic infections among the residents near Pakse, Laos. Korean J Parasitol 36 : 55–58.
  27. Salazar SA, Gutierrez C, Berk SL, 1995. Value of the agar plate method for the diagnosis of intestinal strongyloidiasis. Diagn Microbiol Infect Dis 23 : 141–145.
  28. Van der Feltz M, Slee PH, van Hees PA, Tersme M, 1999. Strongyloides stercoralis infection: how to diagnose best? Neth J Med 55 : 128–131.
  29. Davidson RA, Fletcher RH, Chapman LE, 1984. Risk factors for strongyloidiasis. A case-control study. Arch Intern Med 144 : 321–324.
  30. Nucci M, Portugal R, Pulcheri W, Spector N, Ferreira SB, Braga de Castro M, 1995. Strongyloidiasis in patients with hematologic malignancies. Clin Infect Dis 21 : 675–677.
  31. Berk SL, Verghese A, Alvarez S, Hall K, Smith B, 1987. Clinical and epidemiologic features of strongyloidasis. A prospective study in rural Tennessee. Arch Intern Med 147 : 1257–1261.
  32. Loutfy MR, Wilson M, Keystone JS, Kain K, 2002. Serology and eosinophil count in the diagnosis and management of strongyloidiais in a non-endemic area. Am J Trop Med Hyg 66 : 749–752.
  33. Buchwald D, Lam M, Hooton TM, 1995. Prevalence of intestinal parasites and association with symptoms in Southeast Asian refugees. J Clin Pharm Ther 20 : 271–275.
  34. Graeff-Teixeira C, Leite C, Sperhacke CL, Fassina K, Petry S, Mucenic T, 1997. Prospective study of strongyloidiasis in patients with hematologic malignancies. Rev Soc Bras Med Trop 30 : 355–357.

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  • Received : 24 Feb 2003
  • Accepted : 01 Jul 2003

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