Volume 69, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


A cross-sectional study was undertaken to determine the prevalence of isosporiasis and its clinical and laboratory pattern in Venezuelan patients infected with human immunodeficiency virus (HIV) (n = 397). At enrollment, they underwent a thorough clinical history and physical examination, and provided stool specimens for the identification of and other parasites. was identified in 56 subjects (14%) and diarrhea, either acute or chronic, was present in 98% of these cases ( < 0.001). Eosinophilia was strongly associated with isosporiasis ( = 0.01). It was also found that the presence of eosinophilia was more common in -infected patients without weight loss ( < 0.001). Twenty-six (81.25%) subjects with infection had CD4 cell counts < 200 cells/mm ( = 0.03). In addition, the data and its description shows the association to be < 100 cells/mm. This infection seems to be seasonal because the recovery of oocysts occurred mainly in months with significant rainfall. In fact, isosporiasis should be suspected in HIV-infected patients from tropical countries with diarrhea, weight loss, eosinophilia, and low CD4 cell counts.


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  • Received : 27 Jan 2003
  • Accepted : 29 May 2003

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