1921
Volume 68, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

A total of 1,345 ticks collected from northeastern China were investigated for the presence of and by a nested polymerase chain reaction (PCR). Sixty-two (4.6%) ticks were positive for and 454 (33.8%) were positive for . Seven (0.5%) were coinfected with both agents. Sequence analysis of 919-basepair PCR amplicons revealed three types of . Type 1 was identical to the published sequences of s responsible for human granulocytic ehrlichiosis (HGE). The other two variants differed from the HGE agent sequence at one and four positions, respectively. These findings imply that infection with poses a potential health threat to both humans and animals in northeastern China, and that ehrlichiosis should be considered in the differential diagnosis of febrile patients with a history of tick bite, particularly when clinical manifestations are atypical for Lyme disease.

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2003-05-01
2017-09-22
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  • Received : 20 Jun 2002
  • Accepted : 03 Jan 2003

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