1921
Volume 68, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

A retrospective examination was made of archival data on 98 patient episodes of infection with occurring over a period of 4–11 weeks to document changes in hemoglobin (Hb) concentrations associated with continuing parasitemia. The mean percentage change in the Hb concentration for each of the 10 seven-day intervals was −13.4, −10.9, −4.8, 0.12, 0.94, 4.0, 0.69, 11.6, 2.4, and 8.3, respectively. An equilibrium appeared to be established between weeks 4 and 6. Decreases in Hb concentrations were greatest following the first week of parasitemia. Total restoration to preinfection levels did not occur during persistent parasitemia.

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/content/journals/10.4269/ajtmh.2003.68.410
2003-04-01
2017-09-21
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References

  1. Jakeman GN, Saul A, Hogarth WL, Collins WE, 1999. Anaemia of acute malaria infections in non-immune patients primarily results from destruction of uninfected erythrocytes. Parasitology 119 : 127–133.
  2. Young MD, 1944. Studies on the periodicity of induced Plasmodium vivax. J Natl Malaria Soc 3 : 237–240.
  3. Collins WE, Jeffery GM, 1999. A retrospective examination of sporozoite- and trophozoite-induced infections with Plasmodium falciparum. Am J Trop Med Hyg 61 (Suppl) : 4–48.
  4. Earle WE, Perez M, 1932. Enumeration of parasites in the blood of malarial patients. J Lab Clin Med 17 : 1124–1130.
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  • Received : 15 May 2002
  • Accepted : 26 Dec 2002

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