Volume 68, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


We observed an unusual case of malaria who presented with an initial relapse four years after the primary infection. This occurred in Cameroon, where the patient, a 56-year-old priest, acquired a mild form of malaria and was treated with only chloroquine. Since he returned to Italy, he had not experienced any malaria-like symptoms, had not visited any other areas endemic for malaria, and had not received a blood transfusion. Blood smear microscopy confirmed the presence of . parasites, but unclear morphologic characteristics did not allow discrimination between and . A nested polymerase chain reaction-based molecular analysis identified as the plasmodial species responsible. This case emphasizes the importance of taking into account the possibility of a very late initial relapse of malaria and the relevant issues in terms of infection control.


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  • Received : 28 Jan 2002
  • Accepted : 02 Oct 2002

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