1921
image of A Systematic Literature Review of Microscopy Methods Reported in Malaria Clinical Trials
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Microscopy of stained blood films is essential for the diagnosis of malaria, differentiation of parasite species, and estimation of parasite density performed for assessments of antimalarial drug efficacy. The accuracy and comparability of these measures over time and space are vital to discern the emergence or spread of antimalarial drug resistance. Although evidence-based guidelines for malaria microscopy methods exist, the age-old microscopy techniques for parasitological assessments are subject to considerable methodological variations. The purpose of this review was to explore critically how microscopy methods were reported in published malarial studies between 2013 and 2017 with the focus on outlining the methodological differences and improving reporting standards in practice.

[open-access] This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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/content/journals/10.4269/ajtmh.20-1219
2020-12-21
2021-01-17
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.20-1219
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  • Received : 17 Sep 2020
  • Accepted : 21 Oct 2020
  • Published online : 21 Dec 2020
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