Volume 57, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



The natural history of and infections were determined in a cohort of 164 Bedouin children, from a population not previously studied, which is in transition from nomadism to a settled life style. Stools were sampled monthly from birth to two years of age and at all diarrhea episodes. The risk of infection with and infection by age two was 91.5% and 48.8%, respectively. prevalence was 3–4% at all ages, whereas prevalence was > 30% after age one. and asymptomatic detection rates were high, 28.5% and 1.6%, respectively. Detection of was higher in diarrhea episode samples obtained before six months of age, but after that age and overall, the detection was lower than in nondiarrhea samples (odds ratio [OR] = 0.8, 95% confidence interval [CI] = 0.7–0.9, < 0.05). Detection rates of were higher in episode-related samples in all age groups (OR = 2.8, 95% CI = 1.9–4.2, < 0.05) and infections in boys were more frequently symptomatic than in girls. While does not appear to be a consistent pathogen in this population where it is hyperendemic, has been shown to be an important cause of diarrhea in young children in the community.


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