Volume 47, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



The Lyme disease spirochete was detected in the adult stage of the ixodid ticks and collected in various localities in Japan. The total prevalence values were 16.6% of 777 and 23.6% of 687 . Sixty-two (63.9%) of 97 isolates from contained the 30–34-kD heterogeneous outer surface protein A (A) that reacted with monoclonal antibody H5332. In contrast, all 128 isolates from were homogeneous with regard to the type of 30-kD A protein, and were different from the isolates in their protein composition. These data suggest that the transmission cycle of in is not related to that in . No cases of Lyme disease transmitted by have been confirmed in Japan, in spite of the abundance of human tick bites by this species. Accordingly, the spirochetes of are thought to be a variant of with low virulence.


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