Volume 47, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Microsporidia are very primitive, eukaryotic, obligate, intracellular, protozoan parasites. , a microsporidian originally described from a rabbit infection, has been described in humans as well as in many species of laboratory animals. We report the detection of by Western blotting in a rabbit with torticollis that was obtained from an -free colony. Cross-reactivity of this serum was observed with antigens prepared from several genera of microsporidia. Identical Western blotting patterns were obtained with sera obtained from a rabbit immunized with that was purified from tissue culture cells. In addition, we were able to demonstrate cross-reactivity between rabbit antisera and antigens by indirect immunofluorescent assay techniques in human intestinal biopsy samples. These cross-reactions between microsporidia may be useful in developing diagnostic tests for non-cultivatable microsporidia such as .


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