1921
Volume 47, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Abstract

An analysis of antigen-specific antibodies was performed on 44 serum samples from Guatemala, a region endemic for . Most sera showed positive reactivity to asexual stage antigens by indirect immunofluorescent assay, enzyme-linked immunosorbent assay, and immunoprecipitation analysis using biosynthetically labeled parasites. Although several antigens were recognized by these sera, proteins with molecular weights of 195 kD, 140 kD, and in the range of 70–80 kD were strongly recognized by many of the sera studied. No such reactivity was observed for any of the surface antigens in the male and female gametes and zygotes of . These studies suggest that and , two major human parasites, may share certain epitopes in several antigens of immunologic significance.

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/content/journals/10.4269/ajtmh.1992.47.422
1992-10-01
2017-09-24
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