Volume 47, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


Clinical Studies. The first paper in this section reports on studies by Taiwanese colleagues on the hepatic changes in 270 patients diagnosed as having dengue fever (page 265). The investigators used a battery of biochemical indicators of liver function and concluded that dengue may cause hepatic injury and transaminase elevations similar to those seen in patients with conventional viral hepatitis. The prevalence of ovalocytosis in Malaysian aborigines and its impact on malaria is the subject of a paper starting on page 271. Heavy infections, regardless of the species of , were found only in normocytic persons. Ovalocytosis increases with age, leading to the conclusion that this factor may have a survival advantage in this population. Starting on page 276 is the description of an interesting study on the impact of oral bovine immunoglobulin, with high titers of experimentally produced anti- antibodies on oral challenge with the same agent.


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