1921
Volume 44, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
USD

Abstract

Abstract

The blood schizontocidal activity of α and β arteether has been compared with that of α/β arteether (a 30:70 mixture of α and β isomers), which is a fast-acting blood schizontocide undergoing phase I clinical trials at the Central Drug Research Institute. Both β and α/β arteether have comparable activity and are curative at a dose of 5 mg/kg for 3 days against blood-induced B infection in the rhesus monkey; α arteether alone is slightly less active, with a 50% cure rate at the above dose.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.1991.44.560
1991-05-01
2017-11-19
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1991.44.560
Loading

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error