1921
Volume 43, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
USD

Abstract

Abstract

A new sesquiterpene lactone α/β arteether (a 30:70 mixture of enantiomers), which possesses very high blood schizontocidal activity, has been evaluated for gametocytocidal/sporontocidal action against B infection in the rhesus monkey. This paper reports gametocytocidal action of this new antimalarial drug at 2.5–5 mg/kg (single im dose) against B as shown by the complete absence of mosquito infectivity. No sporontocidal action was demonstrable in the vector at a dose of up to 20–50 mg/kg im.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.1990.43.571
1990-12-01
2017-11-22
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1990.43.571
Loading

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error