Volume 41, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Ultrastructural observations were made of changes in the tegument and reproductive organs of and from ICR mice after treatment with praziquantel (PZQ), levo-PZQ, and dextro-PZQ at a single oral dose of 500 mg/kg body weight. No marked difference in types and extent of lesions of the tegument of was found between the compounds regardless of the time of worm recovery after treatment. This was equally true of . Degeneration of the testis, ovary, and vitelline gland of was more prominent in worms administered PZQ and levo-PZQ than in those receiving dextro-PZQ. In , extensive regression of the reproductive organs was observed in male and female worms treated with PZQ and dextro-PZQ, while no serious damage was seen in worms treated with levo-PZQ.


Article metrics loading...

Loading full text...

Full text loading...


Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error