1921
Volume 40, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Abstract

The surface of amastigote forms of is covered by a stage-specific glycoprotein, Ssp-4. We show that Y strain-derived Ssp-4 is recognized by antibodies in sera from Chagasic patients. All 51 sera reacted with the surface of amastigotes by indirect immunofluorescence assays and immunoprecipitated Ssp-4. The human antibodies inhibited the binding of monoclonal antibodies to Ssp-4 in immunoradiometric assays, suggesting that the corresponding region of the molecule may be conserved among distinct strains of the parasite.

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/content/journals/10.4269/ajtmh.1989.40.46
1989-01-01
2017-09-21
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1989.40.46
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  • Accepted : 12 Aug 1988

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