Volume 39, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



A seroepidemiologic survey of and transmission was conducted in 94 Orang Asli children and adults. The prevalence of malaria was 46% in this population, and infections due to and occurred with equal frequency. Multi-species infection was common, particularly in children <10 years of age. Circumsporozoite (CS) antibodies to were detected by ELISA, using the recombinant protein NS1 V20, in sera from 53–95% of all subjects in this study. The specificity of reactivity to NS1 V20 was confirmed by immunofluorescence using air-dried sporozoites. CS antibodies to were present in <50% of the population <30 years of age. These data support further testing of this protein as a candidate vivax vaccine.


Article metrics loading...

The graphs shown below represent data from March 2017
Loading full text...

Full text loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error