1921
Volume 38, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Abstract

Mass drug administration via 3 modes of delivery reduced the incidence and prevalence rates and intensity of infection in 3 rural villages in the Bengkoka Peninsula, Sabah, in 1982–1983. A dosage of 6 mg diethylcarbamazine citrate (DEC-C)/kg body weight was administered either daily or weekly (total of 6 doses, 36 mg/kg body weight), and impact on cases were comparable in the 3 villages. A total of 384 people participated in the DEC-C regimens, and all pregnant women and children under 2 years were excluded from the study. Bekessy's method of estimation of incidence and recovery rates was applied to data on microfilaremia before drug administration. Treatment with DEC-C by any of the 3 modes of delivery drastically reduced the number of episodes of patent microfilaremia, incidence and prevalence, and median microfilarial density. Reduction was sustained for at least 18 to 24 months after treatment.

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/content/journals/10.4269/ajtmh.1988.38.582
1988-05-01
2017-09-24
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1988.38.582
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  • Accepted : 24 Sep 1987

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