1921
Volume 38, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Abstract

The rate of phosphorylation of 2-deoxyglucose (2DG) was determined by sequential pulsing of schistosomes (male and female ) with [H- and C]-2-deoxy-D-glucose. The relative phosphorylation rate of 2-[H]-2DG to 1-[C]-D-glucose (i.e., the phosphorylation coefficient) was also measured in male and female schistosomes. Even though 2DG is taken up more rapidly than glucose, it is phosphorylated at a much slower rate in . Mated schistosomes phosphorylate 2DG and glucose at a greater rate than do unmated worms. In contrast, the phosphorylation coefficient is greater in separated than mated schistosomes. In schistosomes exposed to oltipraz for short time periods (6 min, at a concentration of 10 µg/ml) glucose utilization rates were significantly reduced in (both mated and separated) female and by a similar magnitude (not significant) in males.

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/content/journals/10.4269/ajtmh.1988.38.342
1988-03-01
2017-11-24
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1988.38.342
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  • Accepted : 04 Aug 1987

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