1921
Volume 37, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Abstract

Renal function was assessed in 101 schoolchildren with active urinary schistosomiasis by measuring serum creatinine, urate, urea, and B-microglobulin, urinary B microglobulin, and the glomerular filtration rate. Glomerular function in all subjects was normal as were serum creatinine, urate, and urea levels. Serum B-microglobulin was elevated in only 8% of subjects while urinary B-microglobulin only was raised in 7% of subjects, indicating proximal tubular dysfunction, a previously unreported feature in urinary schistosomiasis. Urinary tract abnormalities were found in 43% of subjects consenting to an excretory urogram but no correlation with biochemical parameters of renal function was noted. Serum angiotensin converting enzyme level measured in 70 subjects was elevated in 11% of subjects and was regarded as a possible measure of increased granulomatous activity.

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/content/journals/10.4269/ajtmh.1987.37.556
1987-11-01
2017-09-21
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1987.37.556
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  • Accepted : 01 Jun 1987

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