Volume 35, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Tegumentary leishmaniasis is highly prevalent in the Pacific coast region of Colombia. We have identified 90 foci of transmission in this region based on 179 parasitologically diagnosed patients. Human transmission occurred in mangrove forests, secondary growth and intervened tropical rain forest. A parasitological diagnosis, that is, either isolation or visualization of was made in 68.6% of suspected cases. Three phenotypically distinguishable groups of were encountered based on isoenzymes: variants (82%), variants of (14.5%), and stocks intermediate between and reference strains (3.5%). The variants produced cutaneous disease alone relatively infrequently (12% of classified cutaneous stocks) but were more frequently (38% of all mucosal stocks) isolated from mucosal lesions. infection of the mucuous membranes caused a wide spectrum of disease, severity being closely related to time of evolution. Both contiguous and metastatic spread to the mucous membranes was supported by the clinical course of 19 mucosal cases.


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