Volume 35, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



In order to determine if spp. could become infected with the Lyme disease spirochete () by direct inoculation and to determine the duration of spirochetemia, 4 and 5 were inoculated by the intramuscular, intraperitoneal, and subcutaneous routes with an isolate of obtained from the blood of a trapped wild from Camp McCoy, Wisconsin. All of the mice developed antibodies to which reached a peak indirect immunofluorescent (IFA) geometric mean antibody titer of 10 log 21 days post-inoculation. was recovered from the blood of 1 21 days post-inoculation. One uninfected of each species was housed in the same cage with the infected as a contact control. Both of the contact controls developed IFA antibodies by day 14, indicating contact infection. To determine if was being transmitted by direct contact, 5 uninfected and 5 uninfected were caged with 3 infected and 3 infected , respectively. Each of these contact-exposed and developed antibodies to and was isolated from the blood of 1 contact-exposed 42 days post-initial contact. These findings show that can be transmitted by direct contact without an arthropod vector.


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  • Accepted : 12 Oct 1985

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