1921
Volume 35, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Abstract

Serum immunoglobulin (IgG, IgM, IgA) and complement (C, C) levels were measured by radial immunodiffusion technique in a group of 16 Nigerian patients with tropical pyomyositis (TP). Sixteen healthy Nigerians, age- and sex-matched with the patients, were also included in the study as control subjects (CS). A significantly low level of circulating IgM ( < 0.01) and elevation of the serum levels of IgG ( < 0.01) and IgA ( < 0.01) were observed in TP compared to CS. Mean serum complement (C, C) levels were found to be similar in patients and controls. Microbiological culture tests showed that 14 pus specimens (88%) and 3 blood specimens (19%) from the patients were positive for . It was therefore proposed that IgM antibody deficiency (primary or acquired) against may be the cause of tropical pyomyositis in Nigerians.

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/content/journals/10.4269/ajtmh.1986.35.1231
1986-11-01
2017-09-24
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1986.35.1231
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  • Accepted : 23 May 1986

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