1921
Volume 35, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Abstract

Methylbenzethonium chloride (MBCl) decreased the growth of promastigotes and amastigotes in vitro. This decrease occurred during 4 days of exposure to the drug at concentrations of 0.1 to 2.5 µg ml. MBCl at 2 µg ml killed almost 100% of the free living promastigotes and 87% of amastigotes within 4 days of treatment. Electron microscopy studies showed marked swelling of mitochondria in treated parasites. A possible additional effect on the parasite surface membrane is discussed.

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/content/journals/10.4269/ajtmh.1986.35.1110
1986-11-01
2017-11-17
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1986.35.1110
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  • Accepted : 19 Jun 1986

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