Volume 33, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



An immunoradiometric assay (IRMA) using a monoclonal antibody to the major surface protein of sporozoites was used to assess the sporozoite rate in a West African population of (s.l.). Unlike current dissection techniques, the IRMA could detect sporozoite antigen in dried as well as fresh mosquitoes. In a controlled comparison, the sensitivity of the IRMA was comparable that of the dissection technique. Additionally, the IRMA was species specific and quantitative. Sensitivity of the assay was sufficient to detect sporozoite infections resulting from the development of a single oocyst.


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  • Accepted : 04 Jan 1984

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