1921
Volume 33, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
USD

Abstract

Abstract

A study of the course of parasitemia and mortality of C57BL/6 mice infected with the Sylvio-X10 strain and two single-cell-isolate clones of the strain confirms our previous report on the existence of intra-strain subpopulations differing in their pathogenicity for inbred mice. In contrast to the generally accepted pattern of mouse strain susceptibility, C57BL/6 mice are more susceptible than C3H/HeN mice when infected with the Sylvio-X10 isolates. In addition, sex-related differences in susceptibility occurred depending upon the strain of the mouse and parasite isolate used. These data infer an interplay of host and parasite genetic factors influencing the outcome of a mouse infection with .

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.1984.33.236
1984-03-01
2017-09-24
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1984.33.236
Loading
  • Accepted : 22 Sep 1983

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error