1921
Volume 33, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
USD

Abstract

Abstract

Monoclonal antibodies were used to demonstrate antigenic diversity in over 100 primary isolates of collected from one area of Papua New Guinea. The frequencies of several parasite antigens in our sample is calculated. One particular antigen which had previously been shown to be absent in one-third of established isolates collected from several countries appeared ubiquitous in our sample from Papua New Guinea. A method is presented that can be used to test for associations between antigens; the analysis also reveals whether other variables affect these associations. Several associations between antigens were revealed. In one instance, the association between two particular parasite antigens was affected by the donor's age. The importance of characterizing the antigenic structure of populations, and its relevance to the introduction of an antimalarial vaccine are discussed.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.1984.33.204
1984-03-01
2017-09-25
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1984.33.204
Loading
  • Accepted : 29 Sep 1983

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error