Volume 33, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


This is a small paperback book which is designed to be used by physicians who care for patients with sickle-cell disease. It is the first book of its kind written in Africa for Africans. Although aimed at tropical Africa, it will be of use to physicians in other parts of the world where sickle-cell disease occurs. The book consists of nine chapters and three appendices which were written by eight contributing authors including the editor, Dr. A. F. Fleming. All have academic appointments in Nigeria.

The book opens with a historical introduction and an explanation of the molecular biology and the nature of inheritance of hemoglobinopathies. The mathematical basis of population genetics is presented in one page. There are three chapters on the clinical course of sickle-cell disease, one each on the pathology and radiology of the disease and laboratory diagnosis.

The distinguishing feature of this booklet is its conciseness.


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